creation of new psychoactive substances sg report

The topic of this review is complicated due to the frequent abuse of psychotomimetic drugs by patients affected by psychotic disorders, a fact that makes it extremely difficult to distinguish between an induced psychosis and a re-exacerbation of a previously diagnosed disorder. Regarding these newly synthesized substances of abuse, further clinical studies are needed to understand their psychogenic properties.

On the other hand, the progress in terms of pharmacodynamics knowledge has led to the synthesis of new drugs, such as cannabinoids and cathinone's, which have rapidly entered into the common pool of abusers' habits. On one hand, the abuse of methamphetamines, cannabis, and cocaine plays a big role in increasing the incidence of episodes resembling a psychotic disorder. Such psychotic episodes are classified according to the major category of symptoms: positive, negative, or cognitive psychotic episodes. 2Department of Pathophysiology and Transplantation, University of Milan, Milan, Italyīackground: On the current psychopharmacological panorama, the variety of substances able to provoke an episode of acute psychosis is rapidly increasing.

1Department of Neurosciences and Mental Health, Fondazione Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

Alessio Fiorentini 1, Filippo Cantù 2, Camilla Crisanti 2, Guido Cereda 2, Lucio Oldani 1 and Paolo Brambilla 1,2 *

Creation of new psychoactive substances sg report